The purpose of this study was to test the effect of a self-efficacy promotion smoking cessation program for middle school students. This program was redesigned on the basis of Shin Sung Rye(1997)'s Self-Efficacy Promoting Program for this study. The design of this paper was quasi-experimental, equivalent control group pre-post test, time series design. The subjects of this study were 53 smoker adolescents in D Middle School in the city of Busan. The results were summarized as follows: 1) The Hypothesis 1 was accepted : The self efficacy of the experimental group was higher than that of the control group after 1 week (expected efficacy t=2.20, P< .05, expected outcomes t=-2.58, p< .05) 4 weeks after education (expected efficacy t=- .19, P< .001, expected outcomes t=-2.586, p< .05). 2) The Hypothesis 2 was accepted : The amount of smoking of the experimental group was reduced more than that of the control group after 1 week (t=2.05, P< .05) and after 4 weeks (t=2.03, p< .05). 3) The Hypothesis 3 was accepted : The positive urine cotinine of the experimental group was less than that of the control group after 1 week after education(chi2=8.57, P< .01) after 4 weeks (chi2=22.49, P< .001). In conclusion, a self-efficacy promotion smoking cessation program for middle school students was an effective smoking cessation program and then it will be valuable for stopping the smoking among the adolescents.